A Modular, Nanoscale Platform for the Targeted Delivery of Camptothecin to Cancer Cells Expressing TAG-72

4 days ago 13
Biomater. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5BM00788G, Communication
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Reham Hassan, Zirui Zhu, Mingyang Ji, Ziyuan Meng, Emily R. Matas, Damu Sunilkumar, Dario Palmieri, Benjamin A. Conrad, Thomas J. Magliery, Jon Parquette
A camptothecin (CPT)-dilysine nanotube, stabilized with a layer of polydopamine (PDA), was functionalized on the surface with anti-TAG-72 antibody fragments. Cell viability studies showed that the presence of the targeting...
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