Does mechanobiology drive respiratory disease? Biomechanical induction of mucus hypersecretion in human bronchial organoids using a photocontrolled biomaterial gel

1 week ago 26

Biomater. Sci., 2025, Accepted Manuscript
DOI: 10.1039/D5BM00958H, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Isabel Uwagboe, Sharon Mumby, Iain E. Dunlop, Ian M Adcock
Respiratory diseases such as COPD, IPF and severe asthma are major causes of death globally, characterized by chronic inflammation and by fibrotic biomechanical remodelling of the lung ECM. However, present...
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