A thermosensitive hydrogel achieves sustained co-delivery of two therapeutic agents with distinct properties for preventing aseptic loosening

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Biomater. Sci., 2026, Accepted Manuscript
DOI: 10.1039/D6BM00096G, Paper

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Yang Wang, Xin Wang, Hongjie Zhang, Yaoben Wang, Hancheng Wang, Zhiyong Chen, Jiandong Ding, Xiaochun Peng, Lin Yu
Wear particle-induced prosthesis aseptic loosening severely affects the longevity of total joint arthroplasty. This condition arises from periprosthetic osteolysis, which is driven by excessive inflammation and enhanced bone resorption under...
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