Different leukocyte subsets are targeted by systemic and locoregional administration despite conserved nanomaterial characteristics optimal for lymph node delivery

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Biomater. Sci., 2024, Accepted Manuscript
DOI: 10.1039/D4BM00910J, Paper

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&nbsp This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.

Paul A. Archer, Alexander J. Heiler, Alisyn R. Bourque, Yunus Alapan, Susan Napier Thomas
Lymph nodes (LNs) house a large proportion of the body’s leukocytes. Accordingly, engineered nanomaterials are increasingly developed to direct therapeutics to LNs to enhance their efficacy. Yet while lymphatic delivery...
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