Natural product-integrated microneedle patch for rheumatoid arthritis treatment through anti-inflammation and angiogenesis suppression

Biomater. Sci., 2025, Advance Article
DOI: 10.1039/D5BM00036J, Paper

Open Access

&nbsp This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.

Peng Hua, Suleixin Yang, Lin Yu, Yongzhuo Huang, Meiwan Chen
A microneedle patch (B/S-TM@MN) was developed to encapsulate ROS-responsive micelles loaded with berberine and sinomenine, which enhanced the overall anti-arthritis outcome through simultaneous anti-inflammation and anti-angiogenesis.
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